Liver Sourcing

Promethera has a certified GMP manufacturing facility of 7500 sq ft, based in Durham, NC, US. This operation works closely with the U.S. Organ Procurement Organizations (OPO) to obtain healthy, non-transplantable human livers. The Promethera US manufacturing facilities are in compliance with both U.S. and EU GMP regulations. 


The Gift of Life

Organ transplantation is one of the most remarkable success stories in the history of medicine.  But despite the continuing advances in medicine and technology, the need for organs and tissue is vastly greater than the number available for transplantation.  Without the selfless donation of the families of the donors, and the donors themselves, through direct donation, these lifesaving organs would not be available for transplant or the vital research that contributes to lives saved.

Transplantation gives hope to thousands of people with organ failure and provides many others with active and renewed lives.  By becoming an organ donor, you have the power to save lives.

Promethera Biosciences LLC is highly active in the field of organ donation and transplantation as this is in line with our strategy to help people with disease.  Promethera LLC utilizes donated livers which are not suitable for liver transplantation and subsequently recovers high quality liver cells derived from this gift. The cells are then transplanted into patients with liver diseases.  With Promethera LLC’s recovery process, we are able to treat multiple patients from one donated liver and extend the use of this Gift of Life to as many patients as possible. 

Please visit to find out more information about becoming an organ donor.

Making a liver referral

For liver referrals, please dial our call center at 1-877-433-1916

Promethera Organ Procurement Organization Department (OPO)

OPO network in the US

To facilitate clinical trials, as well as commercialization and manufacturing, Promethera has developed partnerships with a network of organ procurement organizations.  Promethera already has developed agreements and outstanding relationships with over 90% of the OPOs in the US to obtain livers for our therapeutic programs.  These partnerships enable Promethera to maintain the highest standard in characteristics and quality of the livers to be accepted for liver cell isolation for our therapeutic programs. The manufacturing team assembled at Promethera has processed in excess of 1,000 livers to date. This represents unrivalled experience in the industry.  

US Organ Procurement Partners

Alabama Organ Center, Arkansas Reg. Organ Recovery Agency, Carolina Donor Services, Donor Network of Arizona, Intermountain Donor Services, Iowa Donor Network, Kentucky Organ Donor Affiliates, Life Connection of Ohio, LifeBanc, LifeCenter Northwest, LifeGift Organ Donation Ctr, LifeLink of Georgia, Center for Organ Recovery and Education, Ctr for Donation and Transplant, Donor Alliance, Donor Network West, Finger Lakes Donor Recovery Network, Gift of Hope, Gift of Life Donor Program, Gift of Life Michigan, Indiana Donor Network, Life Alliance Organ Recovery Agency, LifeCenter Organ Donor Network, LifeChoice Donor Services, Lifeline of Ohio, LifeLink of Florida, LifeLink of Puerto Rico, LifeNet Health, LifeShare of the Carolinas, LifeShare Transplant Donor Svcs of OK, Lifesharing - A Donate Life Org., LifeSource Upper Midwest, LiveOnNY, Louisiana Organ Procurement Agency, Mid-America Transplant Svcs, Mid-South Transplant Foundation, Midwest Transplant Network, Mississippi Organ Recovery Agency, Nebraska Organ Recovery System, Nevada Donor Network, New England Organ Bank, New Mexico Donor Services, New Jersey Organ and Tissue Sharing Network, OneLegacy, Pacific NW Transplant Bank, Sharing Hope South Carolina, Sierra Donor Services, Southwest Transplant Alliance, Tennessee Donor Svcs, Texas Organ Sharing Alliance, The Living Legacy Foundation of Maryland, TransLife, Upstate NY Transplant Svcs, UW Health Organ and Tissue Donation, Washington Reg Transplant Community, Wisconsin Donor Network.

Research Organ Allocation Program

In order to facilitate lifesaving research, which is a goal of each OPO partner, Promethera Biosciences LLC is now helping to place other organs offered for research  with multiple research entities throughout the US.

The Promethera Research Organ Allocation Program  for researcher partners is a critical part of the operation. As a result, Promethera has put in place a fully integrated system for safely providing human organs for research. This includes a thorough researcher vetting protocol to assure all researchers meet OPO ethical standards, mission, and regulatory objectives.

For more information please contact .

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